The scripts and input files that accompany this demo can be found in the demos/public directory of the Rosetta weekly releases.

KEYWORDS: NUCLEIC_ACIDS RNA DENOVO STRUCTURE_PREDICTION

Purpose

This code is intended to give three-dimensional de novo models of single-stranded RNAs or multi-stranded RNA motifs, with the prospect of reaching high (near-atomic-resolution) accuracy.

This test case involves the most conserved region of the signal recognition particle, a 4x4 RNA internal loop.

See the documentation for RNA 3D structure modeling for more information. 

$> $ROSETTA3/bin/rna_denovo.default.linuxgccrelease @flags
where $ROSETTA3=path-to-Rosetta/main/source