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Code and Demo

The executable can be found in Rosetta/main/source/src/apps/public/membrane/mp_domain_assembly.cc

Description

A full description of the algorithm can be found in

  • Koehler Leman, J. & Bonneau, R. A novel domain assembly routine for creating full-length models of membrane proteins from known domain structures. Biochemistry acs.biochem.7b00995 (2017). doi:10.1021/acs.biochem.7b00995

A protocol capture with a zip folder of corresponding files is available in the Supplement of this paper.

The implementation is based on RosettaMP:

  • Alford, R. F., Koehler Leman, J., Weitzner, B. D., Duran, A. M., Tilley, D. C., Elazar, A. & Gray, J. J. An Integrated Framework Advancing Membrane Protein Modeling and Design. PLoS Comput. Biol. 11, e1004398 (2015).

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