RBInMover

Table of Contents

Author

Gideon Lapidoth; glapidoth@gmail.com; Christopher Norn; ch.norn@gmail.com ;PI: Sarel J. Fleishman; sarel@weizmann.ac.il

Overview

Brief

This mover is used to sample different variable light and variable heavy chains orientations for antibody modeling ABpredict) and antibody design (ABdesign). The database is created using the RBOutMover.

<RBIn name="(&string;)" rigid_body_dbase="(&string;)"
        from_entry="(1 &non_negative_integer;)"
        to_entry="(1 &non_negative_integer;)" randomize="(true &bool;)"
        db_entry="(&string;)"
        modify_foldtree="(true &bool;)" />

rigid_body_dbase: path to database file with Vl/Vh orientations.
from_entry: limit range to sample database from
to_entry: limit range to sample database from
randomize: Randomly sample from database.
db_entry: Select specific entry to sample from
modify_foldtree: If true, set a new fold tree with jump between Vl/Vh

Example

Currently, this mover is only accessible via RosettaScripts. An example RosettaScripts tag is below:

<RBIn name="rb" rigid_body_dbase="rb.db" db_entry="1AHW"/>