DesignRandomRegion

Simply chooses random residues from the pose. This task operation is stochastic to allow for variation in design regions. Each call to this operation results in a new randomly selected set of residues chosen for design.

<DesignRandomRegion name="(&string)" region_shell="(&real)" regions_to_design="(&int)" repack_non_selected="(&bool)" />

region_shell: The radius of a sphere that surrounds the residue selected for mutation. All residues within this sphere will be set to design, and all residues outside of it will not be designed.
repack_non_selected: If set, residues outside of the design sphere will be repacked, otherwise they will be fixed.
regions_to_design: The number of residues (and regions based on the value of region_shell) to be selected for design.

Example The following example redesigns a sphere of 8 A radius centered at a randomly selected residue. Residues outside of the sphere are fixed.

<TASKOPERATIONS>
    <DesignRandomRegion name="des_random" region_shell="8.0" regions_to_design="1" repack_non_selected="0" />
</TASKOPERATIONS>
<MOVERS>
    <PackRotamersMover name="design" task_operations="des_random" />
</MOVERS>
<PROTOCOLS>
    <Add mover_name="design" />
</PROTOCOLS>

DesignRandomRegion

DesignRandomRegion

See Also