AspartimidePenaltyEnergy.hh File Reference

This is a score term that penalizes sequences that are likely to result in aspartimide formation during peptide synthesis. More...

#include <core/energy_methods/AspartimidePenaltyEnergy.fwd.hh>
#include <core/chemical/AA.hh>
#include <core/scoring/methods/ContextIndependentLRTwoBodyEnergy.hh>
#include <core/scoring/ScoreFunction.fwd.hh>
#include <core/pose/Pose.fwd.hh>
#include <core/types.hh>
#include <utility/vector1.hh>

Classes
class	core::energy_methods::AspartimidePenaltyEnergy

Namespaces
	core
	A class for reading in the atom type properties.
	core::energy_methods

Detailed Description

This is a score term that penalizes sequences that are likely to result in aspartimide formation during peptide synthesis.

This is intended for peptide design applications only. Sequences penalized are LASP-D*, LASP-LSER, LASP-LTHR, LASP-LGLN, and the mirror-image equivalents (DASP-L*, DASP-DSER, DASP-DTHR, DASP-DGLN), plus D/LASP-GLY.

Author

Vikram K. Mulligan (vmull.nosp@m.ig@u.nosp@m.w.edu)